As science advances, so do the theories that were previously thought to be concrete. Watson and Crick, two renounced scientists in the field of microbiology, do nothing more than follow this pattern in their paper "Nature" by correcting and further developing the previous hypothesis of DNA structure. In their paper, they highly rely on logic as well as strong counterarguments to argue their hypothesis as the most probable. Firstly, their logic shows their strong knowledge of the subject and connects the dots between experimentation and hypothesis for readers. They state that, "It has been found experimentally that the ratio of the amounts of adenine to thymine, and the ratio of guanine to cytosine, are always very close to unity for deoxyribose nucleic acid [...] if an adenine forms one member of a pair, on either chain, then on these assumptions the other member must be thymine; similarly for guanine and cytosine" (Watson and Crick 1). By using hard results from thorough experimentation, Watson and Crick developed a structure that fit with the facts and that is widely accepted as the model for DNA today. The two scientists also argue against previous hypothesis for the structure, such as those of Pauling and Corey. The previous structure was believed to have the phosphate groups facing each other on the interior of the complex, where Watson and Crick point out that, "the negatively charged phosphates near the axis will repel each other" (Watson and Crick 1), and therefore proves the old model to be unrealistic and leads way for their model to take the spotlight. Today, Watson and Crick's model for DNA structure stands soundly in all biology textbooks, and is not likely to be argued against any time in the near future. Clearly, Watson and Crick made a sound argument for their model through unarguable logic and thorough counterarguments.
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